姓名：舒杨
职称：教授
专业：化学
所属二级学科：分析化学
研究方向：生物传感
E-mail: [email protected]
个人简历：
舒杨，女，成人抖音教授，博士生导师，辽宁省“兴辽英才计划”青年拔尖人才。研究方向为生物分子荧光成像、核酸技术传感、纳米诊疗药物等。作为项目负责人承担国家自然科学基金项目4项。在ACS Sensors、Anal Chem、Chem Eng J、Biosens Bioelectron、Carbon等发表SCI论文100余篇，单篇引用200余次。
近年来的主要研究工作：
1. 生物分子荧光成像：合成小分子荧光化合物和荧光纳米材料，特异性成像分析细胞内半胱氨酸、酶、金属离子、线粒体膜电位、pH和温度等。
2. 核酸技术传感：设计DNA、RNA适配体荧光探针，结合等温扩增、CRISPR等放大策略，检测和成像生物样本中的酶和核酸，用于肿瘤细胞的精准识别和区分。
3. 纳米诊疗药物：构建离子液体活性药物成分、离子液体微乳和水凝胶增强药物透皮递送和可控释药；开发金属多酚纳米复合物用于光疗、热疗和化疗等联合治疗。
近年来承担的主要项目（五项）：
作为项目负责人承担国家自然科学基金青年项目1项，面上项目3项，正在主持的科研项目：国家自然科学基金面上项目《RNA辅助金属纳米探针的胞内原位合成与成像》，2022.01-2025.12
近年来发表的代表性论文（十篇）：
1.Xiao-Juan Wang, Chen-Xi Zhao, Na-Na Yin, Xue Wang, Yang Shu*, Jianhua Wang*. A dual miRNAs imaging platform based on HRCA-Cas12a by replacing PAM with bubble to reduce false positive, Analytical Chemistry, 2025, 97, 3053.
2.Na-Na Yin, Chen Wei, Yang Shu*, Jian-Hua Wang*, A nanothermometer with microwave thermal effect for sensing cell membrane temperature and measuring microwave-induced thermal gradient distribution, Analytical Chemistry, 2025, 97, 543.
3.Ying Liu, Tianqi Liu, Zhenye Zhu*, Lin Xie, De Bai, Tonglin Liu, Wenting Gu, Wei Li, Yang Shu*, Jiaheng Zhang*, An advanced hydrogel dressing system with progressive delivery and layer-to-layer response for diabetic wound healing, Acta Biomaterialia, 2024, 190, 79.
4.Wen-Xin Zhang, Lin-Yu Li, Yang Shu*, Jian-Hua Wang *, Coordination catalysis of metal and polydopamine enables controlled release of CO from MnCO by enhancing oxidative stress and thermal effect, Inorganic Chemistry Frontiers, 2024, 11, 5196.
5.Xiao-Juan Wang, Pei-Ying Lv, Chen-Xi Zhao, Na-Na Yin, Teng Fei, Yang Shu*, Jianhua Wang*, A dual amplification strategy integrating entropy-driven circuit with Cas14a for sensitive detection of miRNA-10b, Sensors and Actuators B: Chemical, 2023, 397, 134666.
6.Yi-Ru Gao, Wen-Xin Zhang, Lin-Yu Li, Ze-Jun Wang*, Yang Shu*, Jian-Hua Wang, Ionic liquid-based gels for biomedical applications, Chemical Engineering Journal, 2023, 452: 139248.
7.Na-Na Yin, Bo Lin, Yang Shu*, Jian-Hua Wang*, Nanothermometer with temperature induced reversible emission for evaluation of intracellular thermal dynamics, Analytical Chemistry, 2022, 94, 12111.
8.Qi-Kun Zhang, Xiao-Ping Zhang, Yang Shu*, Jian-Hua Wang*, Metal–organic frameworks encapsulating carbon dots enable fast speciation of mono- and divalent copper, Analytical Chemistry, 2022, 94, 2255.
9.Jian-Fang Cao, Pei-Ying Lv, Yang Shu*, Jian-Hua Wang*, Aptamer/AuNPs encoders endow precise identification and discrimination of lipoprotein subclasses, Biosensors & Bioelectronics, 2022, 196, 113743.
10.Yi-Ru Gao, Ya-Nan Hao, Wen-Xin Zhang, Ya-Nan Wei, Yang Shu*, Jian-Hua Wang*, Microwave-triggered ionic liquid-based hydrogel dressing with excellent hyperthermia and transdermal drug delivery performance, Chemical Engineering Journal, 2022, 429: 131590.
